Restoration of fertility potential via targeted treatment approach
نویسندگان
چکیده
منابع مشابه
Identification of Genes Potentially Associated with the Fertility Instability of S-Type Cytoplasmic Male Sterility in Maize via Bulked Segregant RNA-Seq
S-type cytoplasmic male sterility (CMS-S) is the largest group among the three major types of CMS in maize. CMS-S exhibits fertility instability as a partial fertility restoration in a specific nuclear genetic background, which impedes its commercial application in hybrid breeding programs. The fertility instability phenomenon of CMS-S is controlled by several minor quantitative trait locus (QT...
متن کاملI-6: Fertility Preservation in Male Patient with Cancer
Studies suggest that the ability to have biological children is of great importance to many people. The cancer and its treatment often pose a threat to fertility. Rates of permanent infertility and compromised fertility after cancer treatment vary and depend on many factors. Male infertility can result from the disease itself (best documented in patients with testicular cancer and Hodgkin’s lym...
متن کاملParental attitudes toward fertility preservation in boys with cancer: context of different risk levels of infertility and success rates of fertility restoration.
OBJECTIVE To measure the parental attitudes toward fertility preservation in boys with cancer. DESIGN Retrospective cohort study. SETTING Questionnaire survey via regular mail. PATIENT(S) A total of 465 families whose sons were already treated for cancer. INTERVENTION(S) The questionnaire was designed for two groups based on child's age at the time of cancer diagnosis: <12 and ≥12 years...
متن کاملAB008. Management of fertility post cancer
The successful treatment of males with cancer has led to increasing numbers of men and boys interested in life after cancer. One of the top priorities for many of these males is the opportunity to have a family. Most cancer treatments used for common malignancies in men and boys are associated with impaired fertility; for patients receiving alkylating agents or total body irradiation, severe fe...
متن کاملDevelopment and evaluation of macrophage targeted multidrug therapy against visceral leishmaniasis
In this study, we fabricated PCL-nanoparticles by encapsulating dual drugs as amphotericin B and doxorubicin via double-emulsion solvent evaporation method also incorporated with ligand-lectin for targeting the infested macrophage cells and prove importance against VL. Different independent processing parameters were assessed systematically to enhance the incorporation of the dual agents with d...
متن کامل